RhoA-GTP 小鼠單抗/活性抗體使用說明書及介紹

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GTP酶是GTP/GDP結(jié)合蛋白。被細(xì)胞表面受體(GPCR)激活后, 它能調(diào)節(jié)下游效應(yīng)器的功能。費斯德生物抗體，它可以結(jié)合GTP、水解GTP，因此在激活的GTP結(jié)合狀態(tài)和非激活的GDP結(jié)合狀態(tài)之間切換。它具有內(nèi)在的GTP酶活性，可將GTP水解為GDP，從而使G蛋白失活。我們精心篩選的小鼠單克隆抗體能捕捉到與GTP結(jié)合的具有活性的GTP酶。它們已被用于通過免疫組織化學(xué)監(jiān)測細(xì)胞和組織中 G 蛋白的活化和分布。

描述: Anti-RhoA-GTP Mouse Monoclonal Antibody

背景介紹: Small GTPases are a super-family of cellular signaling regulators. RhoA belongs to the Rho sub-family of GTPases. Rho proteins play critical roles in many actin cytoskeleton- dependent processes including platelet aggregation, cell motility, contraction, and cytokinesis. It regulates the formation of stress fibers and focal adhesions in fibroblasts and Ca 2+ sensitivity of smooth muscle contraction.

免疫原: Recombinant full length protein of active RhoA

經(jīng)過測試的應(yīng)用: IP, IHC,IF

推薦稀釋比: IP: 1 µg for 1~2 mg total cellular proteins IHC, IF: 1:50-1:250

濃度: 1 mg/ml

宿主: Mouse

形式: Liquid

克隆性: Monoclonal

亞型: IgG2b

純度: Purified from ascites

防腐劑: No

成分: PBS (without Mg 2+ and Ca 2+ ), pH 7.4, 150 mM NaCl, 50% glycerol

種屬反應(yīng)性: Anti-RhoA monoclonal antibody recognizes active RhoA from vertebrates.

儲存條件: Store at -20°C. Avoid repeated freezing and thawing

Immunoprecipitation/Western Blot: IP/WB Analysis of Active RhoA Protein. Purified recombinant RhoA proteins were loaded with GDP (lane 1) or GTPγS (lane 2). These proteins were immunoprecipitated with anti-RhoA-GTP monoclonal antibody (Cat. # 26904). After SDS/PAGE, the membrane filter was probed with anti-RhoA mouse monoclonal antibody (Cat. # 26007).

產(chǎn)品說明書和使用介紹：
https://www.neweastwuhan.com/wp-content/uploads/2022/05/26904_RhoA-GTP.pdf

索取資料

來源：武漢費斯德生物科技有限公司
聯(lián)系電話：027-63487286
E-mail：[email protected]

【點擊可查看武漢費斯德生物科技有限公司相關(guān)產(chǎn)品】

標(biāo)簽： RhoA-GTP 小鼠單抗活性抗體鼠單抗

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RhoA-GTP 小鼠單抗/活性抗體使用說明書及介紹