ProSci Incorporated 于1998年成立于世界生物城之一的美國加州圣地亞哥市，從事抗體等科研試劑
的研發(fā)、生產(chǎn)和銷售。 ProSci是世界最早和最大的細(xì)胞凋亡抗體生產(chǎn)廠家和供應(yīng)商，公司現(xiàn)擁有17000
多種單、多克隆抗體，產(chǎn)品涵蓋了細(xì)胞凋亡、信號轉(zhuǎn)導(dǎo)、免疫、腫瘤、細(xì)胞生物、神經(jīng)生物、傳染病等
領(lǐng)域。公司的抗體大都經(jīng)免疫親和層析純化，具有高純度、高親和力、特異性強(qiáng)等特點(diǎn)，所有的ProSci
抗體都經(jīng)過了嚴(yán)格的驗(yàn)證測試和質(zhì)量控制，已保證高質(zhì)量的產(chǎn)品。ProSci的抗體廣銷於世界30多個(gè)國家
和地區(qū)，得到歐美日等生物醫(yī)學(xué)界科研人員和生物制藥公司的研發(fā)人員的廣泛接受。ProSci直銷的產(chǎn)品
和ProSci的名字已在520多篇科研論文中出現(xiàn)了1500多次，ProSci的經(jīng)銷商和客戶都對ProSci產(chǎn)品的質(zhì)量
和服務(wù)十分滿意。我們的抗體可用于免疫印跡（Western blot) ，免疫組織化學(xué)（IHC），免疫細(xì)胞化學(xué)（ICC），酶聯(lián)免疫吸附實(shí)驗(yàn)（ELISA)和細(xì)胞流式分析（FACS)等方面。
此外，ProSci還提供標(biāo)記二抗，重組蛋白，細(xì)胞和組織裂解液，細(xì)胞涂片，組織切片，多肽等產(chǎn)品與抗體配套使用。ProSci在美國擁有完整的免疫學(xué)試劑開發(fā)、生產(chǎn)、檢測的生產(chǎn)線，包括自己的廠房和實(shí)驗(yàn)動物基地，可為您的研究提供信得過的抗體等科研試劑。
 
ProSci 致力于給全世界生物醫(yī)藥領(lǐng)域的科學(xué)家們提供最好的抗體等科研試劑產(chǎn)品，并努力成為他們研究的首選和最好的伙伴。
這是我們一直為之努力的優(yōu)質(zhì)服務(wù)：
·可靠的產(chǎn)品質(zhì)量和全面的說明書
·詳細(xì)準(zhǔn)確且不斷更新的數(shù)據(jù)資料
·豐富的在線資源和全面的技術(shù)支持
·快捷可靠的物流運(yùn)輸
·專業(yè)的技術(shù)人員提供的優(yōu)質(zhì)售后服務(wù)
 
 
質(zhì)量保證，我們的產(chǎn)品應(yīng)用文獻(xiàn)超過520 多篇，品牌名稱在論文上出現(xiàn)1500 多次，客戶中包括美國國立衛(wèi)生研究院（NIH），美國國家疾控中心（CDC），麻省理工學(xué)院（MIT），耶魯大學(xué)以及諾華制藥等許多知名大學(xué)研究機(jī)構(gòu)和制藥公司，國內(nèi)的客戶有：中科院上海生命研究院，中國國家疾控中心，北京協(xié)和醫(yī)院，香港大學(xué)等等。
 
ProSci 產(chǎn)品應(yīng)用文獻(xiàn)統(tǒng)計(jì)數(shù)據(jù)
發(fā)表雜志名稱                             應(yīng)用文獻(xiàn)數(shù)               影響因子
Journal of Experimental medicine                8                      14.77
Journal of Molecular Cell Biology                15                     13.4
Blood                                        24                     10.56
Journal of Cell Biology                         11                      9.92
PNAS                                        19                     9.77
Cancer research                               63                     8.23
Human molecular genetics                      4                       8.01
Nucleic acids research                          3                      7.84
Journal of Neuroscience                        17                      7.27
Journal of Cell science                          8                       6.29
The Journal of Infectious Disease                2                       6.29
Molecular and cellular biology                   6                        6.19
Journal of Immunology                         34                       5.75
The Journal of Biological chemistry               93                       5.33
Molecular cancer therapeutics                   11                       5.22
Journal of Virology                             31                       5.19
Molecular pharmacology                        7                        4.72
Journal of Leukocyte biology                     6                        4.63
Infection and immunity                          4                         4.1
Journal of Bacteriology                          5                        3.73
 
ProSci 2011 年部分最新產(chǎn)品應(yīng)用文獻(xiàn)
1. Mechanisms of necroptosis in T cells. Irene L. Ch’en etc…,J. Exp. Med., Apr 2011; 208: 633 - 641.
Ripk3 antibody (ProSci Inc.).
2. SOX2 promotes tumorigenesis and increases the anti-apoptotic property of human prostate cancer cell
Xianpei Jia etc…,J Mol Cell Biol, Aug 2011; 3: 230 - 238. Antibodies used included polyclonal anti-SOX2, STIM1
(ProSci Inc.), Orai1 (ProSci Inc.).
3. DNA methyltransferase 1, cytosine methylation, and cytosine hydroxymethylation in mammalian mitochondria
Lisa S. Shock etc…, PNAS, Mar 2011; 108: 3630 - 3635. Cells were transfected using Polyjet liposomes (ProSci)
(HCT116).
4. Disruption of Src function potentiates Chk1-inhibitor–induced apoptosis in human multiple myeloma cells in vitro and
in vivo. Yun Dai etc…, Blood, Feb 2011; 117: 1947 - 1957. expression of Bim using an antibody (ProSci).
5. Proteomic analysis identifies galectin-1 as a predictive biomarker for relapsed/refractory disease in classical Hodgkin
lymphoma. Peter Kamper etc…, Blood, Jun 2011; 117: 6638 - 6649.
anti-GNAI3 (XW-7212; WB dilution 1:200 ProSci Incorporated).
3
6. Antiviral memory CD8 T-cell differentiation, maintenance, and secondary expansion occur independently of MyD88
Adeeb H. Rahman etc…, Blood, Mar 2011; 117: 3123 - 3130.
probed with rabbit anti-mouse MyD88 antibody (2127; ProSci).
7. Constitutive BR3 receptor signaling in diffuse, large B-cell lymphomas stabilizes nuclear factor-B–inducing kinase
while activating both canonical and alternative nuclear factor-B pathways
Lan V. Pham etc…,Blood, Jan 2011; 117: 200 - 210. polyclonal BR3 (ProSci).
8. Store-Operated Ca2+ Entry in Sensory Neurons: Functional Role and the Effect of Painful Nerve Injury
Geza Gemes etc…, J. Neurosci., Mar 2011; 31: 3536 - 3549.
anti-STIM1 rabbit polyclonal antibody (1:500; ProSci; catalog #4119), and anti-Orai1 rabbit polyclonal antibody (1:1000;
ProSci, catalog #4281).
9. β-Agonist-associated Reduction in RGS5 Expression Promotes Airway Smooth Muscle Hyper-responsiveness
Zhao Yang etc…, J. Biol. Chem., Apr 2011; 286: 11444 - 11455. anti-RGS5 primary antibody (Prosci, 1:250).
10. Bit-1 Mediates Integrin-dependent Cell Survival through Activation of the NFB Pathway
Genevieve S. Griffiths etc…,J. Biol. Chem., Apr 2011; 286: 14713 - 14723.
rabbit anti-Bit-1 polyclonal antibody (1:100; ProSci) or anti-FAK antibody (1:100; ProSci).
11. Painful Pathways Induced by TLR Stimulation of Dorsal Root Ganglion Neurons
Jia Qi etc…,J. Immunol., Jun 2011; 186: 6417 - 6426.
rabbit polyclonal Ab against TLR3, TLR7, and TLR9 (1:1000; Prosci, Poway, CA).
12. The C Proteins of Human Parainfluenza Virus Type 1 Limit Double-Stranded RNA Accumulation That Would
Otherwise Trigger Activation of MDA5 and Protein Kinase R
Jim Boonyaratanakornkit etc…, J. Virol., Feb 2011; 85: 1495 - 1506.
HPIV1 C proteins shared by C, C Y1, and Y2 by ProSci (Poway, CA), against a synthetic peptide.
13. Phosphorylation of polynucleotide kinase/ phosphatase by DNA-dependent protein kinase and ataxia-telangiectasia
mutated regulates its association with sites of DNA damage
Angela E. Zolner etc…, Nucleic Acids Res., Aug 2011; 10.1093.
phospho-specific antibodies to serine 114, (ProSci Inc).
14. The cyclin-dependent kinase inhibitor p21 is regulated by RNA-binding protein PCBP4 via mRNA stability
Ariane Scoumanne etc…, Nucleic Acids Res., Jan 2011; 39: 213 - 224.
Anti-PCBP4 was from ProSci Incorporated (Poway, CA, USA).
15. Cancer-Associated Loss-of-Function Mutations Implicate DAPK3 as a Tumor-Suppressing Kinase
John Brognard etc…, Cancer Res., Apr 2011; 71: 3152 - 3161.
DAPK3 (ZIPK) antibody was purchased from ProSci Incorporated.
16. MicroRNA-301 Mediates Proliferation and Invasion in Human Breast Cancer
Wei Shi etc…, Cancer Res., Apr 2011; 71: 2926 - 2937.
SKA2 protein was detected using a rabbit anti-SKA2 antibody (ProSci Inc.).