最新Nature刊登的科技文獻指出: 通過比較Sigma,SantaCruz的同類產(chǎn)品, 只有ImmuneChem的抗生物素抗體Agarose填料達到PTM蛋白質(zhì)組學(xué)質(zhì)譜分析應(yīng)用的質(zhì)量。蛋白質(zhì)翻譯后生物修飾是新的PTM研究領(lǐng)域。 抗生物素抗體Agarose填料也是非破壞性(Non-invasive)純化Biotin-tag重組蛋白的重要填料, 可不必用蛋白變性溶液而直接用游離生物素洗脫。 比傳統(tǒng)Avidin, Streptavidin Agarose要理想。
ImmuneChem Biotin Antibody Agarose produced the best results in research article published in: Nature Methods | |
The binding affinity of anti-biotin antibodies could improve the elution of biotinylated peptides. This table shows the difference in the # of unique peptides when samples are biotinylated.
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Biotin antibody compared to non-biotin samples
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Immunechem’s Biotin Antibody Agarose (ICP0615) yielded the highest number of biotinylated peptides compared to Sigma-Aldrich and Santa Cruz. For more details, please refer to: |