FOXBOX呼吸代謝技術(shù)助力右美托咪定治療COVID19重癥患者研究
瀏覽次數(shù):1360 發(fā)布日期:2022-1-27
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據(jù)SSI呼吸代謝技術(shù)官網(wǎng)2022年1月20日最新參考信息,鎮(zhèn)靜劑右美托咪定可能有助于治療重癥監(jiān)護(hù)中的新冠肺炎患者——但它如何影響呼吸和血壓?
右美托咪定可維持一定程度的鎮(zhèn)靜狀態(tài),有利于降低機(jī)體的氧耗率,改善氧合。來自日本牙科大學(xué)的科學(xué)家采用Foxbox呼吸代謝技術(shù)構(gòu)建了如下圖所示的鎮(zhèn)靜
相關(guān)研究成果見2022年1月14日PLOS ONE在線論文“Effect of dexmedetomidine on cardiorespiratory regulation in spontaneously breathing adult rats”。
參考資料
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2.Wearing, O.H., Ivy, C.M., Gutiérrez-Pinto, N. et al. The adaptive benefit of evolved increases in hemoglobin-O2 affinity is contingent on tissue O2 diffusing capacity in high-altitude deer mice. BMC Biol 19, 128 (2021).
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Catherine M.Ivy,
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4.
右美托咪定在臨床麻醉中的優(yōu)勢地位 (baidu.com)
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新冠危重癥患者七點治療經(jīng)驗_醫(yī)師網(wǎng)-《醫(yī)師報》官網(wǎng) (mdweekly.com.cn)