按品牌選擇
|
|
|||||||||||||||||||||||||||||||||
| [發(fā)表評(píng)論] [本類其他產(chǎn)品] [本類其他供應(yīng)商] [收藏] | ||||||||||||||||||||||||||||||||||
| 銷售商： 北京啟維益成科技有限公司 | 查看該公司所有產(chǎn)品 >> |
| Catalogue Number | CYT-527 |
| Synonyms | VEGF-C, Vascular endothelial growth factor C, VRP, Flt4 ligand, Flt4-L, Vascular endothelial growth factor-related protein, VEGFC. |
| Introduction | VEGF-C, also known as Vascular Endothelial Growth Factor Related Protein (VRP), is a recently discovered VEGF growth factor family member that is most closely related to VEGF-D. Human VEGF-C cDNA encodes a pre-pro-protein of 416 amino acids residues. It is almost identical to the mouse VEGF-C protein. Similar to VEGF-D, VEGF-C has a VEGF homology domain spanning the middle third of the precursor molecule and long N- and C-terminal extensions. In adults, VEGF-C is highly expressed in heart, placenta, ovary and small intestine. Recombinant human VEGF-C, lacking the N- and C-terminal extensions and containing only the middle VEGF homology domain, forms primarily non-covalently linked dimers. This protein is a ligand for both VEGFR-2/KDR and VEGFR-3/FLT-4. Since VEGFR-3 is strongly expressed in lymphatic endothelial cells, it has been postulated that VEGF-C is involved in the regulation of the growth and/or differentiation of lymphatic endothelium. Although recombinant human VEGF-C is also a mitogen for vascular endothelial cells, it is much less potent than VEGF-A. |
| Description | VEGF-C Human Recombinant- contains 129 amino acids residues and was fused to a His- tag (6x His) at the C-terminal end. As a result of glycosylation VEGF-C migrates as an 18-24 kDa protein in SDS-PAGE under reducing conditions. |
| Source | Sf9, Insect Cells. |
| Physical Appearance | Sterile Filtered White lyophilized (freeze-dried) powder. |
| Formulation | Each mg of VEGF-C Human contains 50mg BSA and 1xPBS as buffer. |
| Solubility | It is recommended to reconstitute the lyophilized VEGF-C in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions. |
| Stability | Lyophilized VEGF-C although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution VEGF-C should be stored at 4°C between 2-7 days and for future use below -18°C. Please prevent freeze-thaw cycles. |
| Purity | Greater than 90.0% as determined by(a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE. |
| Biological Activity | Measured by its ability to bind to the VEGFR-3/FLT-4 receptor in the Ba/F3-hVEGFR-3 assay. The ED50 in this assay is about 4ng/ml corresponding to a Specific Activity of 250,000IU/mg. |
| Usage | Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. |
手機(jī)版：VEGF C Human
- 中喬新舟限時(shí)促銷：買細(xì)胞就送支原體檢測(cè)試劑盒
- 華威中儀試劑盒年末限時(shí)優(yōu)惠來(lái)襲，儲(chǔ)值享好禮
- 美德聲推出新品重組細(xì)胞系用于生產(chǎn)單克隆血型試劑
- 百螢小麥胚芽凝集素探針染料8折優(yōu)惠，買即贈(zèng)鼠標(biāo)墊
- 上海惠誠(chéng)生物成為安普未來(lái)恒溫?cái)U(kuò)增試劑盒代理商
- 雙11科研狂歡促銷，逐典攜手埃澤思下單滿額雙重好禮
- MCE 第三屆細(xì)胞攝影大賽圓滿落幕，評(píng)選結(jié)果公布
- MCE教師節(jié)直播:細(xì)胞凋亡的機(jī)制、標(biāo)志物與檢測(cè)方法
- 大鼠肺泡巨噬細(xì)胞(NR8383)培養(yǎng)要點(diǎn)
- 干細(xì)胞誘導(dǎo)生成類器官的工藝要點(diǎn)淺析
- 細(xì)胞復(fù)蘇的原理、實(shí)驗(yàn)步驟及注意事項(xiàng)
- 10個(gè)獲批干細(xì)胞新藥IND及細(xì)胞療法應(yīng)用案例分享
- 寵物干細(xì)胞行業(yè)技術(shù)服務(wù)體系及在治療中的應(yīng)用
- 《人臍帶間充質(zhì)干細(xì)胞治療膝骨性關(guān)節(jié)炎臨床應(yīng)用指南》內(nèi)容及適用范圍
- 免疫B細(xì)胞的分類、活化機(jī)制、主要功能及在疾病治療中的應(yīng)用
- 自然殺傷細(xì)胞（NK細(xì)胞）的功能及培養(yǎng)流程
Copyright(C) 1998-2025 生物器材網(wǎng) 電話：021-64166852;13621656896 E-mail：info@bio-equip.com