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FGF 23 C-term Human
英文名稱:FGF 23 C-term Human總訪問:267
國產(chǎn)/進(jìn)口:進(jìn)口半年訪問:3
產(chǎn)地/品牌:prospec產(chǎn)品類別:細(xì)胞生物學(xué)試劑
規(guī)       格:CYT-028 最后更新:2024-12-5
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Catalogue Number CYT-028
Synonyms Tumor-derived hypophosphatemia-inducing factor, HYPF, ADHR, HPDR2, PHPTC, FGF23, FGF-23, Fibroblast Growth Factor-23.
Introduction FGF-23 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF-23 inhibits renal tubular phosphate transport. This gene was identified by its mutations associated with autosomal dominant hypophosphatemic rickets (ADHR), an inherited phosphate wasting disorder. Abnormally high level expression of FGF23 was found in oncogenic hypophosphatemic osteomalacia (OHO), a phenotypically similar disease caused by abnormal phosphate metabolism. Mutations FGF23 have also been shown to cause familial tumoral calcinosis with hyperphosphatemia.
Description FGF-23 C-term Protein is 8.67 kDa protein containing 72 amino acid residues and an additional 9 a.a. His-Tag at N-terminus.
Source E. coli
Formulation FGF-23 C-term was filtered (0.4µm) and lyophilized from 0.5 mg/ml supplied in 20mM TRIS and 50mM NaCl, pH 7.5.
Solubility It is recommended to add deionized water to prepare a working stock solution of approximately 0.5mg/ml and let the lyophilized pellet dissolve completely. Product is not sterile! Please filter the product by an appropriate sterile filter before using it on cell culture.
Stability Store lyophilized FGF 23 C-term at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted FGF 23 C-term can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C.
Amino Acid Sequence MKHHHHHHAS AED­DSERDPL NVLKPRARMT PAPASCSQEL PSAEDNSPMA SDPLGVVRGG RVNTHAGGTG PEGCRPFAKF I.
Quality Control Test BCA - to determine content of the protein.
SDS PAGE - to determine purity of the protein.
Applications Western blotting
Usage ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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