综合图区亚洲网友自拍|亚洲黄色网络|成人无码网WWW在线观看,日本高清视频色视频kk266,激情综合五月天,欧美一区日韩一区中文字幕页

English | 中文版 | 手機(jī)版 企業(yè)登錄 | 個(gè)人登錄 | 郵件訂閱
當(dāng)前位置 > 產(chǎn)品目錄 > 試劑 > 細(xì)胞生物學(xué)試劑 > TNFR1 Human, His
TNFR1 Human, His
英文名稱:TNFR1 Human, His總訪問:255
國產(chǎn)/進(jìn)口:進(jìn)口半年訪問:3
產(chǎn)地/品牌:prospec產(chǎn)品類別:細(xì)胞生物學(xué)試劑
規(guī)       格:CYT-673 最后更新:2024-12-5
貨       號(hào):
CAS   號(hào):
參考報(bào)價(jià):詢價(jià)
立即詢價(jià) 電話咨詢
[發(fā)表評(píng)論] [本類其他產(chǎn)品] [本類其他供應(yīng)商] [收藏]
銷售商: 北京啟維益成科技有限公司 查看該公司所有產(chǎn)品 >>
  • 產(chǎn)品介紹
  • 公司簡介
Catalogue Number CYT-673
Synonyms Tumor necrosis factor receptor superfamily member 1A, Tumor necrosis factor receptor 1, Tumor necrosis factor receptor type I, TNF-R1, TNF-RI, TNFR-I, p60, p55, CD120a, TNFRSF1A, TNFAR, TNFR1, FPF, TBP1, TNF-R, p55-R, TNFR55, TNFR60, TNF-R-I, TNF-R55, MGC19588.
Introduction TNFR1 belongs to the TNF-receptor superfamily. TNFR1 is a receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha.
There are 2 types of soluble TNF receptors: sTNFR-I and sTNFR-II, which act to neutralize the biological activities of TNF alpha and TNF beta. The levels of these soluble receptors seem to increase as a result of shedding of the extracellular domains of the membrane bound receptors. TNF-a, TNFR1 and TNFR2 have roles in cellular differentiation. TNFR1 and TNFR2 function in cell type-specific renal injury.
TNFR1 is capable of signaling both cell survival and apoptosis. TNFR1-induced apoptosis requires 2 sequential signaling complexes. TNFR1 is capable of activating NF-kappaB, mediate apoptosis, and function as a regulator of inflammation. Oxidative stress promotes TNFR1 and TNFR2 self-interaction, ligand-independent and enhanced ligand-dependent TNF signaling. TNFR1 contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase. Human TNFR1 has a major region which controls cell surface expression. High levels of soluble TNF receptors are found in the amniotic fluid of pregnant women.
Germline mutations of the extracellular domains of TNFR1 are linked to the autosomal dominant periodic fever syndrome. The impaired receptor clearance is believed to be a mechanism of the disease. Familial hibernian fever (FHF) is caused by defects in TNFRSF1A gene.
Description TNFR1 Human Recombinant produced in E.Coli is a single, non-glycosylated, Polypeptide chain containing 161 amino acids fragment (41-201) having a molecular weight of 22.68kDa and fused with a 4.5kDa amino-terminal hexahistidine tag. The TNFR1, His Tag is purified by proprietary chromatographic techniques.
Source Escherichia Coli.
Physical Appearance Sterile Filtered clear solution.
Formulation TNFR1 His Tag protein is supplied in 1xPBS, 50% glycerol.
Stability Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
Please avoid freeze thaw cycles.
Purity Greater than 95.0% as determined by SDS-PAGE.
Amino Acid Sequence

DSVCPQGKYIHPQNNSICCTKCHKGTYLYNDCPGPGQ
DTDCRECESGSFTASENHLRHCLSCSKCRKEMGQVE
ISSCTVDRDTVCGCRKNQYRHYWSENLFQCFNCSLCL
NGTVHLSCQEKQNTVCTCHAGFFLRENECVSCSNCKK
SLECTKLCLPQIEN.

Usage ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
>
bio-equip.com
售后服務(wù)
相關(guān)視頻
資料下載
快速詢價(jià) 請(qǐng) 登錄注冊(cè)在線詢價(jià) (請(qǐng)留下您的聯(lián)系方式,以便供應(yīng)商聯(lián)系您)
* 姓  名:
* 地  區(qū):
* 單  位:
職  位:
* 手機(jī)/電話:
* E-mail:
請(qǐng)寄產(chǎn)品資料:
需要 不需要
請(qǐng)報(bào)價(jià)格:
需要報(bào)價(jià) 不需要報(bào)價(jià)
留  言:
驗(yàn)證碼:
換一張
發(fā)表評(píng)論在線評(píng)論(0條)
手機(jī)版:TNFR1 Human, His
搜索本類產(chǎn)品

更多瀏覽該公司同類產(chǎn)品
您最近瀏覽過的產(chǎn)品
Copyright(C) 1998-2025 生物器材網(wǎng) 電話:021-64166852;13621656896 E-mail:info@bio-equip.com
立即詢價(jià)