Recombinant Human BMP-5
產(chǎn)品編號:
120-39
別名:
none
描述:
TGF-β family members are
key modulators of cell proliferation, differentiation, matrix synthesis, and
apoptosis. As implied by their name, BMPs initiate, promote, and regulate the
development, growth and remodeling of bone and cartilage. In addition to this role,
BMPs are also involved in prenatal development and postnatal growth, remodeling
and maintenance of a variety of other tissues and organs. BMP-5 is
expressed in the nervous system, lung and liver. It is a known regulator
for dendritic growth in sympathetic neurons. BMP-5 is a 454 amino acid
precursor protein that is cleaved to release the biologically active C-terminal
mature protein. Recombinant human BMP-5 is a 15.6 kDa homodimeric
disulfide-linked protein consisting of two identical 138 amino acid chains.
氨基酸序列:
AANKRKNQNR NKSSSHQDSS RMSSVGDYNT SEQKQACKKH ELYVSFRDLG WQDWIIAPEG YAAFYCDGEC SFPLNAHMNA TNHAIVQTLV HLMFPDHVPK PCCAPTKLNA ISVLYFDDSS NVILKKYRNM VVRSCGCH
來源:
CHO cells
純度:
Greater than 95% by SDS-PAGE gel and HPLC analyses.
生物活性:
Determined by its ability to induce alkaline
phosphatase production by ATDC-5 cells. The expected ED50 for
this effect is 0.5-1.0 μg/ml.
原產(chǎn)國:
USA
僅用于研究。不適用于診斷或治療。
