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CAS No. : 41340-25-4

MCE 國際站：Etodolac

產(chǎn)品活性：Etodolac (AY-24236) 是非甾體抗炎化合物，對(duì) COX 的 IC₅₀為53.5 nM。

研究領(lǐng)域：Immunology/Inflammation

作用靶點(diǎn)：COX

In Vitro: Post-marketing studies demonstrated that etodolac inhibition of cyclooxygenase is somewhat COX-2 selective similar to celecoxib and other "COX-2 inhibitors." Unlike rofecoxib, both etodolac and celecoxib can fully inhibit COX-1 and are designated as having "preferential selectivity" toward COX-2. The (inactive against COX) r-enantiomer of etodolac inhibits beta-catenin levels in hepatoma cells.

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