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Focus鹽酸芬戈莫德162359-56-0惠誠(chéng)優(yōu)勢(shì)供應(yīng)
英文名稱(chēng):2-Amino-2-[2-(4-octylphenyl)ethyl]-1,3-propanediol hydrochloride總訪問(wèn):252
國(guó)產(chǎn)/進(jìn)口:進(jìn)口半年訪問(wèn):1
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規(guī)       格:5mg 最后更新:2025-1-2
貨       號(hào):10-2138
CAS   號(hào):162359-56-0
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鹽酸芬戈莫德 2-Amino-2-[2-(4-octylphenyl)ethyl]-1,3-propanediol hydrochloride,CAS號(hào):162359-56-0:,分子式:C19H33NO2 HCl,分子量:343.94 上海惠誠(chéng)生物現(xiàn)貨提供。
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Cat. Number
10-2138
Chemical Name
2-Amino-2-[2-(4-octylphenyl)ethyl]-1,3-propanediol hydrochloride
CAS Number
162359-56-0
Mol. Formula
C19H33NO2 HCl
Mol. Weight
343.94
Qty 1
5mg
Qty 2
25mg
Appearance
White solid
Application Notes
98% by TLC NMR (Conforms)
Synonym
Fingolimod
Solubility
Soluble in DMSO (up to 100 mg/ml) or in Ethanol (up to 40 mg/ml with warming).
Storage condition
-20°C (des.)
Stability
Stable for 1 year as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
References

FTY720 HCl (162359-56-0) is an analog of sphingosine (Cat.# 10-2287) which, when taken up into cells, is phosphorylated and acts as an agonist at sphingosine-1-phosphate receptors (S1P1/3).1 Potently inhibits regulatory T cell proliferation in vitro and in vivo.2 FTY720 HCl enhances microvascular remodeling via expansion of arterioles and capillary networks.3 Potent immunomodulator.4

References/Citations
1) Brinkmann et al. (2002), The immune modulator FTY720 targets spingosine-1-phosphate receptors; J. Biol. Chem., 277 21453
2) Wolf et al. (2009), The sphingosine 1-phosphate receptor agonist FTY720 potently inhibits regulatory T cell proliferation in vitro and in vivo; J. Immunol., 183 3751
3) Awojoodu et al. (2013), Sphingosine 1-phosphate receptor 3 regulates recruitment of anti-inflammatory monocytes to microvessels during implant arteriogenesis; Proc. Natl. Acad. Sci. USA,110 13785
4) Chiba (2005), FTY720, a new class of immunomodulator, inhibits lymphocyte egress from secondary lymphoid tissues and thymus by agonistic activity at sphingosine 1-phosphate receptors; Pharmacol. Ther., 108 308

Focus Biomolecules supplier, chemical structure of FTY720 HCl | Sphingosine-1-phosphate receptor agonist | CAS 162359-56-0

FTY720 HCl ,貨號(hào)10-2138 上;菡\(chéng)提供5mg 25mg FTY720 HCl,美國(guó)focus原裝進(jìn)口,咨詢(xún)電話(huà)17715331663

特色產(chǎn)品:

纖維二糖Cellobiose 100g 500g 1kg

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D-來(lái)蘇糖原料 1kg D-Lyxose

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