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【中文名稱(chēng)】:信號(hào)傳導(dǎo)蛋白SMAD2 多克隆抗體
【英語(yǔ)名稱(chēng)】:Smad2 Polyclonal Antibody
【產(chǎn)品類(lèi)型】:一抗
【供應(yīng)商】:Abbkine
【產(chǎn)品貨號(hào)】:ABP52460
【產(chǎn)品規(guī)格】:30ul/100ul/200ul
【背景資料】:Mothers against decapentaplegic homolog 2 encoded by SMAD4 belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transduc and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation. Alternatively spliced transcript variants encoding the same protein have been observed.
蛋白別名為:SMAD2; MADH2; MADR2; Mothers against decapentaplegic homolog 2; MAD homolog 2; Mothers against DPP homolog 2; JV18-1; Mad-related protein 2; hMAD-2; SMAD family member 2; SMAD 2; Smad2; hSMAD2;基因ID為:4087;蛋白質(zhì)ID:Q15796
【應(yīng)用類(lèi)型】:WB,ELISA
補(bǔ)充:最優(yōu)的抗體稀釋比例需要基于客戶(hù)實(shí)驗(yàn)進(jìn)行優(yōu)化.建議的起始稀釋比例如下: WB: 1:500-1:2000, ELISA: 1:10000. Not yet tested in other applications.
【免疫原】:合成多肽:human Smad2 around the non-phosphorylation site of S255.
【來(lái)源宿主】:兔
【反應(yīng)性】:人,小鼠,大鼠
【保存建議】:廠(chǎng)家推薦藍(lán)冰運(yùn)輸.在發(fā)貨后能在-20℃保存1年.為最大限度的避免損失,請(qǐng)?jiān)诖蜷_(kāi)管蓋之前融化抗體并離心.我們建議使用前分裝以避免反復(fù)凍融.
本產(chǎn)品為液體形式,溶解于PBS緩沖液中,含50%甘油,0.5%BSA和0.02%疊氮化鈉.
【產(chǎn)品說(shuō)明】:點(diǎn)擊:信號(hào)傳導(dǎo)蛋白SMAD2 多克隆抗體查看更詳細(xì)產(chǎn)品說(shuō)明,更多應(yīng)用、儲(chǔ)存、價(jià)格、貨期等信息請(qǐng)致電400-6800-868垂詢(xún)Abbkine中國(guó)區(qū)域授權(quán)總代理艾美捷科技有限公司。更多特色試劑盒、特色抗體以及特色試劑等產(chǎn)品評(píng)論,請(qǐng)點(diǎn)擊查看每日生物評(píng)論網(wǎng)站。
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產(chǎn)品標(biāo)簽:信號(hào)傳導(dǎo)蛋白SMAD2,信號(hào)傳導(dǎo)蛋白SMAD2ABP52460,Sgo1 Polyclonal Antibody,信號(hào)傳導(dǎo)蛋白SMAD2 多克隆抗體,Smad2 Polyclonal Antibody