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銷售商: 北京啟維益成科技有限公司 | 查看該公司所有產(chǎn)品 >> |
Catalogue Number | CYT-312 |
Synonyms | HBGF4, FGF-4, FGF4, KFGF, HSTF1. |
Introduction | FGF4 holds s comprehensive mitogenic and cell survival activities and takes part in a range of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF4 possess oncogenic transforming activity. FGF4 and FGF3, oncogenic growth factors are localized on chromosome 11. Co-amplification of both factors was found in several kinds of human tumors. FGF4 functions in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway. |
Description | FGF4 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 177 amino acids (31-206) and having a molecular mass of 19kDa. The FGF4 is purified by proprietary chromatographic techniques. |
Source | Escherichia Coli. |
Physical Appearence | Sterile Filtered White lyophilized (freeze-dried) powder. |
Formulation | The FGF4 protein was lyophilized with 0.5xPBS, pH 7.5. |
Solubility |
It is recommended to reconstitute the lyophilized FGF4 Human Recombinant sterile 18M?-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions. |
Stability | Lyophilized FGF4 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution FGF-4 should be stored at 4°C between 2-7 days and for future use below -18°C. Please prevent freeze-thaw cycles. |
Purity | Greater than 90.0% as determined by SDS-PAGE. |
Amino Acid Analysis | MAPTAPNGTL EAELERRWES LVALSLARLP VAAQPKEAAV QSGAGDYLLG IKRLRRLYCN VGIGFHLQAL PDGRIGGAHA DTRDSLLELS PVERGVVSIF GVASRFFVAM SSKGKLYGSP FFTDECTFKE ILLPNNYNAY ESYKYPGMFI ALSKNGKTKK GNRVSPTMKV THFLPRL. |
Usage | ProSpecs products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. |
Biological Activity |
The ED50, as determined by its ability to induce the proliferation of mouse NR6R-3T3 fibroblasts, is typically 0.25-1.25 ng/ml, corresponding to a specific activity of 800,000-4,000,000 units/mg. |