product information

background
 
Transferrin is a single polypeptide chain glycoprotein and is a member of the iron binding family of proteins. It has a molecular weight of 77 kDa and a serum concentration range of 1800 to 2700 mg/L. It is synthesised in the liver and consists of two domains, each having a high affinity reversible binding site for Fe3+. The iron is transported in blood and interstitial fluids to sites of use and disposal. Iron/transferrin is essential in haemoglobin synthesis and for certain types of cell division. Serum concentration rises in iron deficiency and pregnancy and falls in iron overload, infection and inflammatory conditions. The function of transferrin is to transport iron from the intestine, reticuloendothelial system, and liver parenchymal cells to all proliferating cells in the body. In addition to its function in iron transport, this protein may also have a physiologic role as granulocyte/pollen binding protein (GPBP) involved in the removal of certain organic matter/allergins from serum.


immunogen
 
human transferrin AAB22049


antibody format
 



goat
polyclonal,

affinity purified,
liquid





quantity
 



1 mg






storage
 
2-8 °C.


tested applications
 
This antibody is suitable for all immunoassay applications.


related products
 

IMS02-020-322 | TF | Transferrin, hen antibody

IMS06-020-323 | TF | Transferrin labelled with biotin, hen antibody

additional information
 
To be added when available.

application information

recommended dilution
 
The optimal working dilution should be determined by the investigator.


expected | apparent MW
 
77 kDa


confirmed reactivity
 
human transferrin


predicted reactivity
 
primates


not reactive in
 
no confirmed exceptions from predicted reactivity known in the moment


additional information
 

Affinity purified using solid phase human Transferrin. Antibody concentration is > 4.5 mg/ml (E 1% at 280 nm = 13.0).

Antibody is supplied in 10 mM sodium phosphate, 0.15 M sodium chloride, pH 7.2. Contains 0.05% (w/v) sodium azide as preservative. Antibody purity is > 95% based on SDS-PAGE.

selected references
 
to be added when available

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