|
|
|||||||||||||||||||||||||||||||||
| [發(fā)表評論] [本類其他產(chǎn)品] [本類其他供應(yīng)商] [收藏] | ||||||||||||||||||||||||||||||||||
| 銷售商： 北京啟維益成科技有限公司 | 查看該公司所有產(chǎn)品 >> |
product information
background
Oxidative derivate of guanosine is called 8-Hydroxyguanosine (8OHdG) and is used as a popular biomarker of oxidative stress.
immunogen
8-hydroxy-guanosine-BSA and – casein conjugates
antibody format
mouse
monoclonal
IgG2A (clone 15A3)
liquid
quantity
25 µg
storage
store at -20°C; avoid repeated freeze-thaw cycles. Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from lyophilized material adhering to the cap or sides of the tubes.
tested applications
ELISA (ELISA), immunostaining on frozen tissue and paraffin-embedded (IHC-Fr-P), affinity purification (AP)
related products
AS10 708-100 | hydroxy guanosine monoclonal antibody, 100 µg
additional information
protein G purified IgG2B in PBS, pH 7.4 with 0.09 % sodium azide and 50 % glycerol at concentration 0.65 mg/ml
application information
recommended dilution
needs to be determined for each application
expected | apparent MW
n.a.
confirmed reactivity
Recognizes markers of oxidative damage to DNA (8-hydroxy-2’-deoxyguanosine, 8-hydroxyguanine and 8-hydroxyguanosine)
predicted reactivity
does not apply
not reactive in
no confirmed exceptions from predicted reactivity known in the moment
additional information
protocol for immunostaining using this antibody can be found here
selected references
Pilger & Rudiger (2006). 8-Hydroxy-2'-deoxyguanosine as a marker of oxidative DNA damage related to occupational and environmental exposures. Int Arch Occup Environ Health. 1: 1-15.
Kowluru et al. (2006). Role of mitochondrial superoxide dismutase in the development of diabetic retinopathy.Invest Ophthalmol Vis Sci 4: 1594-9.
Kim et al. (2003). Mutagenicity of reactive oxygen and nitrogen species as detected by co-culture of activated inflammatory leukocytes and AS52 cells. Carcinogenesis 2: 235-241.
Cui et al. (2000). Oxidative DNA damage precedes DNA fragmentation after experimental stroke in rat brain. Faseb J. 14(7): 955-67.
||| For applications or usage on species others than stated above Agrisera offers a payment-after-testing option. To learn more about this or for any questions on this product, please use the LiveChat option in the left menue bar or contact us at support@agrisera.com
Save as PDF
