近年來(lái)，外泌體的研究熱度持續(xù)攀升，已成為當(dāng)前生命科學(xué)和基礎(chǔ)醫(yī)學(xué)研究的一大熱點(diǎn)。數(shù)據(jù)顯示，在 2023 年國(guó)家自然科學(xué)基金獲批項(xiàng)目中，外泌體研究相關(guān)項(xiàng)目的總數(shù)近 390 個(gè)，立項(xiàng)的總金額突破 1.5 億元。

       近日，Quantum Design中國(guó)順利將NanoView全自動(dòng)外泌體熒光檢測(cè)分析系統(tǒng)安裝于重慶大學(xué)醫(yī)學(xué)院，并為用戶進(jìn)行了詳細(xì)的儀器介紹和操作培訓(xùn)。我們相信設(shè)備優(yōu)異的外泌體表征性能和Quantum Design中國(guó)專業(yè)的技術(shù)團(tuán)隊(duì)將助力重慶大學(xué)醫(yī)學(xué)院在外泌體領(lǐng)域的研究取得重要進(jìn)展！

重慶大學(xué)醫(yī)學(xué)院

       全自動(dòng)外泌體熒光檢測(cè)分析系統(tǒng)是一款無(wú)需純化、全自動(dòng)的可對(duì)單個(gè)外泌體進(jìn)行表征分析的全新設(shè)備。該設(shè)備能夠提供全面的外泌體表征信息，包括外泌體粒徑大小、計(jì)數(shù)、分布、攜帶蛋白表達(dá)、生物標(biāo)志物（CD9，CD81，CD63等）共定位等。設(shè)備操作簡(jiǎn)單，結(jié)果可靠，有效降低了實(shí)驗(yàn)操作難度，提高了實(shí)驗(yàn)效率。短短三年，在世界范圍內(nèi)已有100多家實(shí)驗(yàn)室采用該設(shè)備，包括了著名的哈佛大學(xué)、約翰霍普金斯大學(xué)、康奈爾大學(xué)、洛杉磯兒童醫(yī)院、麻省總醫(yī)院、東京工業(yè)大學(xué)、首爾大學(xué)、新加坡國(guó)立大學(xué)、大阪大學(xué)、北京大學(xué)、上海交通大學(xué)、西安交通大學(xué)、中國(guó)海洋大學(xué)、重慶大學(xué)等，發(fā)表SCI已超過(guò)280篇，其中不乏頂級(jí)期刊如Cell、Nature、Journal   of Extracellular Vesicles、Cancer Research、Nanoscale、ACS Nano、BMJ journal、Brain Behavior Immunity、Trends in Cancer等。

全自動(dòng)外泌體熒光檢測(cè)分析系統(tǒng)安裝完成

Quantum Design中國(guó)工程師向客戶講解實(shí)驗(yàn)原理

NanoView全自動(dòng)外泌體熒光檢測(cè)分析系統(tǒng)測(cè)試數(shù)據(jù)

近三年Exoview高水平文章精選列表：

• Jingjing Zhang   Eduardo …& Reátegui. (2023) Engineering a tunable micropattern-array   assay to sort singleextracellular vesicles and particles to detect RNA and   protein in situ. Journal of Extracellular Vesicles.

• Benjamin Cappe   …& Franck B. Riquet. (2023) Systematic compositional analysis of exosomal   extracellular vesicles produced by cells undergoing apoptosis, necroptosis   and ferroptosis. Journal of Extracellular Vesicles.

• Kotb Abdelmohsen   …& Myriam Gorospe. (2023) urvey of organ-derived small extracellular   vesicles and particles (sEVPs) to identify selective protein markers in mouse   serum. Journal of Extracellular Vesicles.

• Sara Hassanpour   Tamrin …& Arindom Sen. (2023) Critical considerations in determining the surface charge of small extracellular vesicles. Journal of Extracellular Vesicles.

• Gijung Kwak   …& Jung Soo Suk. (2023) Extracellular vesicles enhance pulmonary   transduction of stably associated adeno-associated virus following   intratracheal administration. Journal of Extracellular Vesicles.

• Andras Saftics  …& Tijana Jovanovic-Talisma. (2023) Single Extracellular VEsicle Nanoscopy. Journal of Extracellular Vesicles.

• Richard J. R. Kelwick …& Paul S. Freemont. (2023) Opportunities to accelerate extracellular vesicle research with cell-free synthetic biology. Journal of Extracellular Vesicles.

• Laurence Blavier …& Yves A. DeClerck. (2023) The capture of extracellular vesicles endogenously released by xenotransplanted tumours induces an inflammatory reaction in the premetastatic niche. Journal of Extracellular Vesicles.

• Hongyun Wang ……& Junjie Xiao. (2022) Extracellular vesicles enclosed-miR-421 suppresses air pollution (PM2.5)-induced cardiac dysfunction via ACE2 signalling. Journal of Extracellular Vesicles.

• Linglei Jiang……& Santosh Dhakal. (2022) A7 bacterial extracellular vesicle-based intranasal vaccine against SARS-CoV-2 protects against disease and elicits neutralizing antibodies to wild-type and Delta variants. Journal of extracellular vesicles.

• Shaobo Ruan, Nina Erwin, Mei He. (2022) Light-induced high-efficient cellular production of immune functional extracellular vesicles. Journal of extracellular vesicles.

• Nasibeh Karimi ……&  Cecilia Lässer. (2022) Tetraspanins distinguish separate extracellular vesicle subpopulations in human serum and plasma – Contributions of platelet extracellular vesicles in plasma samples. Journal of Extracellular Vesicles.

• Heikki Kyykallio ……& Pia R-M Siljander. (2022) A quick pipeline for the isolation of 3D cell culture-derived extracellular vesicles. Journal of Extracellular Vesicles.

• Roberto Frigerio ……& Marina Cretich. (2022) Comparing digital detection platforms in high sensitivity immune-phenotyping of extracellular vesicles. Journal of Extracellular Vesicles.

• Yael Hirschberg ……& Inge Mertens. (2022) Characterizing extracellular vesicles from individual low volume cerebrospinal fluid samples, isolated by SmartSEC. Journal of Extracellular Vesicles.

• Sukhbir Kaur……& David D. Roberts. (2022) Single vesicle analysis of CD47 association with integrins and tetraspanins on extracellular vesicles released by T lymphoblast and prostate carcinoma cells. Journal of Extracellular Vesicles.

• Simone M. Crivelli……& Erhard Bieberich. (2022) Function of ceramide transfer protein for biogenesis andsphingolipid composition of extracellular vesicles. Journal of Extracellular Vesicles.

• Gi Beom Kim …& In-San Kim. (2023) Harnessing Oncolytic Extracellular Vesicles for Tumor Cell-Preferential Cytoplasmic Delivery of Misfolded Proteins for Cancer Immunotherapy. Small.

• J. Klein, Y. Cao. (2023) Multi-Lipid Synergy In Cartilage Lubrication: Redundancy Or Evolution? Osteoarthritis and Cartilage.

• Valerie DeLuca …& Michael E. Berens. (2023) Extracellular vesicles as a pharmacodynamic reporter in glioblastoma. Cancer Research.

• Sarah Pike …& Liya Xu. (2023) Extracellular vesicles in diagnostic retinoblastoma aqueous humor correlate with disease stage and clinical outcome: a pilot study. Cancer Research.

• D. Cookson …& Y. Ashraf Kharaz. (2023) The Biological Response Of Anterior Cruciate Ligamentocytes Following Treatment With Synovial Fluid Extracellular Vesicles. Osteoarthritis and Cartilage.

• Mei Lu …& Yuanyu Huang. (2023) Antitumor synergism between PAK4 silencing and immunogenic phototherapy of engineered extracellular vesicles. Acta Pharmaceutica Sinica B.

• Luke C. McIlvenna ……& Martin Whitham. (2023) Single vesicle analysis reveals the release of tetraspanin positive extracellular vesicles into circulation with high intensity intermittent exercise. The Journal of Physiology.

• Joseph Blommer ……& Dimitrios Kapogiannis. (2023) Extracellular vesicle biomarkers for cognitive impairment in Parkinson’s disease. BRAIN.

• Tyler J ……& Atta Behfar. (2022) Exosome biopotentiated hydrogel restores damaged skeletal muscle in a porcine model of stress urinary incontinence. Npj Regenerative Medicine.

• Min Han ……& Tao Xin. (2022) Three-Dimensional-Cultured MSC-Derived Exosome-Hydrogel Hybrid Microneedle Array Patch for Spinal Cord Repair. Nano Letters.

• Zijian Yang ……& David A. Issadore. (2022) Ultrasensitive Single Extracellular Vesicle Detection Using High Throughput Droplet Digital Enzyme-Linked Immunosorbent Assay. Nano Letters.

服務(wù)推出至今，短短兩年時(shí)間已經(jīng)助力多個(gè)中國(guó)客戶發(fā)表高水平文獻(xiàn)！

■ 南方醫(yī)科大學(xué)在《Chemical Engineering Journal》發(fā)表文章

■ 南方醫(yī)科大學(xué)珠江醫(yī)院在《Bioengineering & Translational Medicine》發(fā)表文章

■ 上海大學(xué)在《Journal of extracellular vesicles》發(fā)表文章

■ 中國(guó)科學(xué)院深圳先進(jìn)技術(shù)研究院在《Lab on a Chip》發(fā)表文章

■ 北京天壇醫(yī)院、國(guó)家納米科學(xué)中心、北京航空航天大學(xué)在《Advanced Science》發(fā)表文章

■ 同濟(jì)大學(xué)附屬上海市肺科醫(yī)院、上海思路迪轉(zhuǎn)化醫(yī)學(xué)團(tuán)隊(duì)在《Journal of Nanobiotechnology》發(fā)表文章

■ 山東千佛山醫(yī)院在《NANO LETTERS》發(fā)表文章

■ 陜西師范大學(xué)在《Food & Function》發(fā)表文章

■ 南京大學(xué)在《Frontiers in Cell and     Developmental Biology》發(fā)表文章

■ 中山大學(xué)在《ACS NANO》發(fā)表文章

■ 北京理工大學(xué)在《Acta Pharmaceutica   Sinica B》發(fā)表文章

■ 中南大學(xué)湘雅二醫(yī)院在《International Journal of Nanomedicine》發(fā)表文章

樣機(jī)體驗(yàn)：

       為了更好的服務(wù)中國(guó)客戶，Quantum Design 中國(guó)子公司在北京建立了專業(yè)的客戶服務(wù)中心，正式推出專業(yè)的全面外泌體表征測(cè)試服務(wù)，您只需要極少量樣品即可獲得全面的外泌體表征數(shù)據(jù)！歡迎各位老師垂詢！

相關(guān)產(chǎn)品

1、全自動(dòng)外泌體熒光檢測(cè)分析系統(tǒng)

2、ExoView外泌體全面表征試劑盒