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179 次 FAK 通過 Drp1 調控心肌細胞線粒體裂變和功能 2024-12-16
FAK regulates cardiomyocyte mitochondrial fission and function through Drp1Keywords: Drp1; FAK; fibronectin; mitochondrial fission.線粒體對于心肌細胞的能量產生至關重要，其功能障礙與
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222 次 機械應力經TGF-β1 激活 Smad2/3 并抑制 NF-κB 以防軟骨細胞焦亡 2024-12-16
Mechanical stress protects against chondrocyte pyroptosis through TGF-β1-mediated activation of Smad2/3 and inhibition of the NF-κB signaling pathway in an osteoarthriti
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244 次 動脈粥樣硬化中血流紊亂會損害MerTK介導的主動脈內皮細胞的胞葬作用 2024-12-9
Disturbed flow impairs MerTK-mediated efferocytosis in aortic endothelial cells during atherosclerosisKeywords: Disturbed flow; MerTK; RNA-seq; atherosclerosis; efferocytosis; prot
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218 次 機械敏感的多囊蛋白1促進骨膜干/祖細胞在骨折愈合中的骨軟骨分化 2024-12-9
Mechanosensitive protein polycystin-1 promotes periosteal stem/progenitor cells osteochondral differentiation in fracture healingKeywords: Fracture healing; Mechanical stress; Peri
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252 次 TNFSF12/TWEAK調節(jié)結腸炎性成纖維細胞并促其與單核細胞相互作用 2024-12-2
The TNFSF12/TWEAK Modulates Colonic Inflammatory Fibroblast Differentiation and Promotes Fibroblast-Monocyte InteractionsKWS：TNFSF12/TWEAK；Colonic Inflammatory Fibroblast；Differ
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243 次 miR-342-5p通過抑制 MYC增強內皮細胞對剪切力的動脈化響應 2024-12-2
miR-342-5p downstream to Notch enhances arterialization of endothelial cells in response to shear stress by repressing MYCKeywords: MT: Non-coding RNAs; Notch; arterialization; end
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292 次 激活的SIRT1 通過增強 H 型血管生成和骨形成的耦聯(lián)來促進骨修復 2024-11-25
SIRT1 activation promotes bone repair by enhancing the coupling of type H vessel formation and osteogenesisKWS：SIRT1；bone repair；type H vessel formation；osteogenesis骨缺損可由感
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316 次 血管內皮細胞機械敏感基因在動脈粥樣硬化形成和治療中的研究進展 2024-11-25
Recent advances of mechanosensitive genes in vascular endothelial cells for the formation and treatment of atherosclerosisKeywords: Atherosclerosis; Blood flow; Endothelial cell; M
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358 次 CD97 在壓縮下通過 Rap1a/ERK 通路抑制破骨細胞分化 2024-11-18
CD97 inhibits osteoclast differentiation via Rap1a/ERK pathway under compressionSubject terms: Orthodontics, Cell signalling正畸治療是通過正畸牙齒移動（OTM）矯正咬合不正。OTM 是一種
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504 次 Piezo1 介導的機械轉導導致血流紊亂誘導的動脈粥樣硬化內皮炎癥 2024-11-18
Piezo1‐Mediated Mechanotransduction Contributes to Disturbed Flow‐Induced Atherosclerotic Endothelial InflammationKeywords: Piezo1; atherosclerosis; endothelial cells; inflammati
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244 次 綠茶化合物EGCG在子癇前期的體外靜態(tài)和剪切應力模型中的抗氧化作用 2024-11-16
EGCG, a Green Tea Compound, Increases NO Production and Has Antioxidant Action in a Static and Shear Stress In Vitro Model of PreeclampsiaKeywords: EGCG; NO; antioxidant; endotheli
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361 次 電壓門控性鈣通道α2δ亞基-1調控結腸癌進展并影響其微環(huán)境 2024-10-28
CACNA2D1 regulates the progression and influences the microenvironment of colon cancerKeywords: CACNA2D1; Colon cancer; Fibroblast; Voltage-gated calcium channel; p53.近年來，由于化
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339 次 人牙周膜間充質基質細胞通過旁分泌和細胞接觸介導對CD4+T的免疫調節(jié) 2024-10-28
Paracrine- and cell-contact-mediated immunomodulatory effects of human periodontal ligament-derived mesenchymal stromal cells on CD4+ T lymphocytesKeywords: CD4+ T lymphocytes; Co-
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366 次 衰老誘導內皮受損金屬蛋白酶17脫落連接粘附分子-A導致動脈重塑 2024-10-28
Aging-induced impaired endothelial wall shear stress mechanosensing causes arterial remodeling via JAM-A/F11R shedding by ADAM17Keywords: Aging; Endothelium dysfunction; F11R; Junc
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372 次 BACH1 基因的缺失通過減少內皮炎癥減輕動脈粥樣硬化 2024-10-28
Deletion of BACH1 Attenuates Atherosclerosis by Reducing Endothelial InflammationKeywords: BACH1; YAP; atherosclerosis; endothelial inflammation; hemodynamics.動脈粥樣硬化是冠狀動脈
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260 次 流體剪切應力通過NKG2D增強自然殺傷細胞對循環(huán)腫瘤細胞的細胞毒性 2024-10-25
Fluid shear stress enhances natural killer cell's cytotoxicity toward circulating tumor cells through NKG2D-mediated mechanosensingTopics：Mechanical stress, Cytotoxicity, Degr
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285 次 與體外循環(huán)相關剪切應力誘導單核細胞炎性細胞因子和壞死性凋亡的表達 2024-10-25
Shear stress associated with cardiopulmonary bypass induces expression of inflammatory cytokines and necroptosis in monocytesKeywords: Calcium signaling; Cardiology; Cytokines; Inf
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260 次 線粒體蛋白去琥珀�；ㄟ^調節(jié)線粒體穩(wěn)態(tài)介導壓縮誘導的椎間盤退變 2024-10-25
SIRT5-related desuccinylation modification of AIFM1 protects against compression-induced intervertebral disc degeneration by regulating mitochondrial homeostasisSubject terms: Dise
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404 次 電壓門控性鈣通道α2/δ亞基-1調控結腸癌的進展并影響結腸癌的微環(huán)境 2024-10-21
近年來，由于化療的進步和分子靶向藥物的出現，結腸癌（CC）的治療結果有所改善。離子轉運體（Ion transporters）在細胞功能中起著至關重要的作用，近年來作為癌癥的潛在治療靶點而受到關注。闡
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397 次 衰老致內皮剪切應力感損去整合素金屬蛋白酶介導粘附分子脫落動脈重塑 2024-10-21
隨著年齡的增長，心血管系統(tǒng)發(fā)生了重要變化，包括血管硬度升高和異常重塑。研究表明，與衰老相關的小阻力動脈重塑可以獨立于全身血壓的變化而發(fā)生。研究已表明，小阻力動脈會因血流的持久變化或