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7172 次利用等離子體處理優(yōu)化3D打印PEEK植入物的細胞反應 2024-2-26
聚醚醚酮（PEEK）因其出色的機械性能和生物相容性，在牙科和骨科植入領域得到廣泛應用。盡管如此，PEEK的生物惰性表面限制了其與骨組織的有效結(jié)合。傳統(tǒng)上，通過涂覆羥基磷灰石（HA）等生物活性
191 次 FAK 通過 Drp1 調(diào)控心肌細胞線粒體裂變和功能 2024-12-16
FAK regulates cardiomyocyte mitochondrial fission and function through Drp1Keywords: Drp1; FAK; fibronectin; mitochondrial fission.線粒體對于心肌細胞的能量產(chǎn)生至關重要，其功能障礙與
234 次機械應力經(jīng)TGF-β1 激活 Smad2/3 并抑制 NF-κB 以防軟骨細胞焦亡 2024-12-16
Mechanical stress protects against chondrocyte pyroptosis through TGF-β1-mediated activation of Smad2/3 and inhibition of the NF-κB signaling pathway in an osteoarthriti
246 次動脈粥樣硬化中血流紊亂會損害MerTK介導的主動脈內(nèi)皮細胞的胞葬作用 2024-12-9
Disturbed flow impairs MerTK-mediated efferocytosis in aortic endothelial cells during atherosclerosisKeywords: Disturbed flow; MerTK; RNA-seq; atherosclerosis; efferocytosis; prot
220 次機械敏感的多囊蛋白1促進骨膜干/祖細胞在骨折愈合中的骨軟骨分化 2024-12-9
Mechanosensitive protein polycystin-1 promotes periosteal stem/progenitor cells osteochondral differentiation in fracture healingKeywords: Fracture healing; Mechanical stress; Peri
253 次 TNFSF12/TWEAK調(diào)節(jié)結(jié)腸炎性成纖維細胞并促其與單核細胞相互作用 2024-12-2
The TNFSF12/TWEAK Modulates Colonic Inflammatory Fibroblast Differentiation and Promotes Fibroblast-Monocyte InteractionsKWS：TNFSF12/TWEAK；Colonic Inflammatory Fibroblast；Differ
244 次 miR-342-5p通過抑制 MYC增強內(nèi)皮細胞對剪切力的動脈化響應 2024-12-2
miR-342-5p downstream to Notch enhances arterialization of endothelial cells in response to shear stress by repressing MYCKeywords: MT: Non-coding RNAs; Notch; arterialization; end
296 次激活的SIRT1 通過增強 H 型血管生成和骨形成的耦聯(lián)來促進骨修復 2024-11-25
SIRT1 activation promotes bone repair by enhancing the coupling of type H vessel formation and osteogenesisKWS：SIRT1；bone repair；type H vessel formation；osteogenesis骨缺損可由感
321 次血管內(nèi)皮細胞機械敏感基因在動脈粥樣硬化形成和治療中的研究進展 2024-11-25
Recent advances of mechanosensitive genes in vascular endothelial cells for the formation and treatment of atherosclerosisKeywords: Atherosclerosis; Blood flow; Endothelial cell; M
229 次 TFF切向流過濾系統(tǒng)在外泌體分離中的應用 2024-11-22
外泌體是直徑為30-150 nm的小細胞外囊泡。在生理和病理條件下，幾乎所有類型的細胞都可以釋放外泌體，在細胞通訊和表觀遺傳調(diào)控中發(fā)揮重要作用。外泌體天然存在于體液中，包括血液，唾液，尿液和
360 次 CD97 在壓縮下通過 Rap1a/ERK 通路抑制破骨細胞分化 2024-11-18
CD97 inhibits osteoclast differentiation via Rap1a/ERK pathway under compressionSubject terms: Orthodontics, Cell signalling正畸治療是通過正畸牙齒移動（OTM）矯正咬合不正。OTM 是一種
509 次 Piezo1 介導的機械轉(zhuǎn)導導致血流紊亂誘導的動脈粥樣硬化內(nèi)皮炎癥 2024-11-18
Piezo1‐Mediated Mechanotransduction Contributes to Disturbed Flow‐Induced Atherosclerotic Endothelial InflammationKeywords: Piezo1; atherosclerosis; endothelial cells; inflammati
246 次綠茶化合物EGCG在子癇前期的體外靜態(tài)和剪切應力模型中的抗氧化作用 2024-11-16
EGCG, a Green Tea Compound, Increases NO Production and Has Antioxidant Action in a Static and Shear Stress In Vitro Model of PreeclampsiaKeywords: EGCG; NO; antioxidant; endotheli
378 次使用染料PHK 26進行體外細胞的標記和追蹤 2024-11-7
各類染料在實驗室中非常常用！本期我們將為大家介紹 PKH 26，一種用于體外細胞標記和追蹤的優(yōu)質(zhì)染料！讓我們結(jié)合實際案例，看看科研大佬們是如何利用 PKH 26 進行細胞研究的~本期要和大家分享的
363 次電壓門控性鈣通道α2δ亞基-1調(diào)控結(jié)腸癌進展并影響其微環(huán)境 2024-10-28
CACNA2D1 regulates the progression and influences the microenvironment of colon cancerKeywords: CACNA2D1; Colon cancer; Fibroblast; Voltage-gated calcium channel; p53.近年來，由于化
340 次人牙周膜間充質(zhì)基質(zhì)細胞通過旁分泌和細胞接觸介導對CD4+T的免疫調(diào)節(jié) 2024-10-28
Paracrine- and cell-contact-mediated immunomodulatory effects of human periodontal ligament-derived mesenchymal stromal cells on CD4+ T lymphocytesKeywords: CD4+ T lymphocytes; Co-
367 次衰老誘導內(nèi)皮受損金屬蛋白酶17脫落連接粘附分子-A導致動脈重塑 2024-10-28
Aging-induced impaired endothelial wall shear stress mechanosensing causes arterial remodeling via JAM-A/F11R shedding by ADAM17Keywords: Aging; Endothelium dysfunction; F11R; Junc
374 次 BACH1 基因的缺失通過減少內(nèi)皮炎癥減輕動脈粥樣硬化 2024-10-28
Deletion of BACH1 Attenuates Atherosclerosis by Reducing Endothelial InflammationKeywords: BACH1; YAP; atherosclerosis; endothelial inflammation; hemodynamics.動脈粥樣硬化是冠狀動脈
265 次流體剪切應力通過NKG2D增強自然殺傷細胞對循環(huán)腫瘤細胞的細胞毒性 2024-10-25
Fluid shear stress enhances natural killer cell's cytotoxicity toward circulating tumor cells through NKG2D-mediated mechanosensingTopics：Mechanical stress, Cytotoxicity, Degr
286 次與體外循環(huán)相關剪切應力誘導單核細胞炎性細胞因子和壞死性凋亡的表達 2024-10-25
Shear stress associated with cardiopulmonary bypass induces expression of inflammatory cytokines and necroptosis in monocytesKeywords: Calcium signaling; Cardiology; Cytokines; Inf

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